In my studies on eukaryotic PPINs I am trying to decipher the reasons behind the high connectivity of “hub” nodes. To explain the promiscuity (w.r.t. the number of interactions) of these nodes a new paradigm has been introduced. It was found that the high degree nodes in the eukaryotic PPINs on an average have higher number of splice variants.

I have also worked in collaboration with other labs in CDFD to determine the reasons behind the deleterious mutations of the ARSB gene which lead to Maroteaux Lamy syndrome.

1. Anupam Sinha and H.A.Nagarajaram (2011) Studies on Protein-Protein Interactions: A New Frontier in Computational Biology (key note address) in "Proceedings of 2nd International Conference on Metacomputing 15-16, Dec. 2011, Goa, India" Editor: Dr. P.K.Roy, Allied Publishers Pvt. Ltd., New Delhi.
   
   
2. Anupam Sinha and H.A.Nagarajaram (2013) Effect of Alternative Splicing on the Degree Centrality of nodes in PPI networks of Homo sapiens, J.Proteome Res. 12: 1980-1988.
   
   
3. Anusha Uttarilli, Prajnya Ranganath, S. Jamal Md Nurul Jain, Krishna Prasad C, Anupam SinhaIshwar C Verma, Shubha R Phadke, Ratna D Puri, Sumita Danda, Mamta Muranjan, Ganesh Jevalikar, H A Nagarajaram, Ashwin B Dalal (2014) Novel mutations of the ARSB gene in Indian patients with Mucopolysaccharidosis Type VI, Indian Journal of Medical Research (Accepted)
   
   
4. Anupam Sinha and H.A. Nagarajaram (2014)Nodes occupying central positions in human tissue specific PPI networks are enriched with many splice variants. ProteomicsDOI: 10.1002/pmic.201400249.
   
   

1. "Production of Activated Carbon from Waste Rubber Tires" at Vijayanagar Engineering College (Bellary, 12-13 September 2003), Shristi Techno-Management Fair (P.E.S.I.T, Bangalore, 5 – 8 June 2003) & React (R.V.C.E, Bangalore 10 June 2003).
   
   
2. "Biological Fuel Cells" at Confluence (B.M.S.C.E, Bangalore, June 2003) & Technoscope (S.D.M. College of Engg. and Tech, Dharwad, 13^th May 2003 ).
   
   
3. Presented a poster titled "Characterization of HUBS in the PPI Networks of Homo sapiens"at Indo-French Bioinformatics Meeting, Hyderabad, 23-25 March 2011.
   
   
4. Presented a poster titled "Characterization of Degree Centrality of Nodes in Protein-Protein Interaction (PPI) Networks of Eukaryotes with respect to the Phenomenon of Alternative Splicing"at European Conference of Computational Biology (ECCB), Basel, 9-12 September 2012.
   
   
5. Presented a poster titled "Effect of Alternative Splicing on the Degree Centrality of Nodes in Eukaryotic PPI Networks" at International Conference on Biomolecular Forms and Functions, Bangalore, 8-11 January 2013.
   
   
6. Presented a poster titled "Effect of Alternative Splicing on the Degree Centrality of Nodes in Eukaryotic PPI Networks" at EMBO-Indiabioscience Young Investigator Network Meeting, Bangalore, 7-10 November 2013.
   
   
7. Attended the workshop on "Computational approaches for predicting molecular interactions",October 9-12, 2007 IMTECH, Chandigarh.
   
   
8. Attended the National Symposium on Cellular and Molecular Biophysics, January 22-24, 2009, CCMB, Hyderabad.
   
   
9. Undertook Certificationcourse in Java Programming Language (May-July2009) from APTECH
   
   
10. Attended the 8^th Asia Pacific Bioinformatics Conference, Jan 18-21, 2010, IISC/NCBS, Bangalore.
    
    
11. Attended the workshop "Scientific Computing with Python" organised by FOSSEE, IIT Bombay & EnhanceEdu, IIIT-Hyderabad, February 9-10, 2010 at EnhanceEdu IIIT-Hyderabad.
    
    
12. Attended the workshop on "Topics in Quantitative Genetics and Genome Analysis"on 28^th August 2010 at CCMB, Hyderabad.
    
    
13. Attended the workshop on "Introduction to Mathematical Techniques in Life Sciences" organized by IISc Mathematical Initiative (IMI), January 04-12, 2011, at IISc, Bangalore.
    
    
14. Attended the "Science and Communication Workshop" organized by the Wellcome Trust/DBT India Alliance, August 24-26, 2011.
    
    
15. Attended the workshop Hands-On Training: Implementing NGS for Genomics and Epigenetics studies 24^th-27^th February, 2014.