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Dr. H.A.Nagarajaram
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Home » Computational Biology » Publications
Computational Biology
Publications of Dr.Nagarajaram
  1. Suresh B. Mudunuri, Priyatosh Mishra and H.A. Nagarajaram (2012) Distributional Analysis and Motif Frequencies of Compound Microsatellite Repeats in Viral Genomes. IEEE International Conference on Computing, Electronics & Electrical Technologies (ICCEET), 2012 (Accepted) (will become available in IEEE digital library)

  2. Anupam Sinha and H.A.Nagarajaram (2011) Studies on Protein-Protein Interactions: A New Frontier in Computational Biology (key note address) in "Proceedings of 2nd International Conference on Metacomputing 15-16, Dec. 2011, Goa, India" Editor: Dr. P.K.Roy, Allied Publishers Pvt. Ltd., New Delhi

  3. M D Bashyam, A K Chaudhary, E C Reddy, V Reddy, V Acharya, H A Nagarajaram, A R R Devi, L Bashyam, A B Dalal, N Gupta, M Kabra, M Agarwal, S R Phadke, R Tainwala, R Kumar, S V Hariharan (2011). An Ectodysplasin A receptor (EDAR)founder mutation results in a high frequency of the autosomal recessive form of Hypohidrotic Ectodermal Dysplasia in India. Br J Dermatol (In Press).

  4. Md. Tabrez Shamim and H A Nagarajaram (2011) A Hierarchical Approach to Protein Fold Recognition J. Integr. Bioinform. 8:185-, 2011 (online journal http://journal.imbio.de/index.php?paper_id=185)

  5. Vishal Acharya and H.A.Nagarajaram (2012) Hansa: An automated method for discriminating disease and neutral human nsSNPs Hum Mutat 33 332-337

  6. Murali Bashyam, Guroji Purushotham, Ajay K Chaudhary, Madhumohan Rao, Vishal Acharya, Tabrez Mohammad, Hampapatalu Nagarajaram, Vuppaladadhiam Hariram, Calambur Narasimhan(2011). A low prevalence of MYH7/MYBPC3 mutations among Familial Hypertrophic Cardiomyopathy patients in India. Mol Cell Biochem. 00:000-000; in press.

  7. Md. Tabrez Shamim and H A Nagarajaram (2011) SVM-Based method for protein structural class prediction using secondary structural content and structural information of amino acids J.Bioinform. Comput. Biol 9: 489-502

  8. Pankaj Kumar, P. S. Chitanya and H A Nagarajaram (2011) PSSRdb: A Relational Database of Polymorphic Simple Sequence Repeats Extracted from Prokaryotic Genomes Nucleic Acid Res. 39(suppl 1): D601-D605

  9. Suresh B Mudunuri, Pankaj Kumar, Allam Appa Rao, S Pallamsetty and H A Nagarajaram (2010) G-IMEx: A comprehensive software tool for detection of microsatellites from genome sequences Bioinformation 5: 221-223

  10. G Purushotham, K Madhumohan, Mohammad Anwaruddin,H.A Nagarajaram,Vuppaladadhiam Hariram,Calambur Narasimhan,Murali D Bashyam.(2010) the MYH7 p.R787H mutation causes hypertrophic cardiomyopathy in two unrealted families.Exp clin Cardial 2010;15(1):e1-e4.

  11. Thoh, M., Kumar, P., Nagarajaram, H.A. and Manna, S.K. (2010)Azadirachtin interacts with the TNF binding domain of its receptors and inhibits TNF-induced biological responses J. Biol. Chem. (in Press; published December 14, 2009 as doi:10.1074/jbc.M109.065847)

  12. Suresh, B.M, Rao, A.P, Mishra, P. and Nagarajaram, H.A. (2010) . Comparative Analysis of Microsatellite Detecting Software: A Significant Variation in Results and Influence of Parameters, Proceedings of International Symposium on Biocomputing, (ISB 2010), Kerala, February 15-17, 2010. (Link to ACM Digital Library)

  13. Suresh B. Mudunuri, Allam Appa Rao, S Pallamsetty, Priyatosh Mishra and H.A.Nagarajaram (2009) VMD: Viral Microsatellite Database - A Comprehensive Resource for All Viral Microsatellites. Journal of Computer Science and Systems Biology. 22: 283-000. doi:10.4172/jcsb.1000043: 001-004

  14. Korupolu, R.V., Achary, M.S., Aneesa, F., Sathish, K., Wasia, R., Sairam, M., Nagarajaram, H.A. and Singh, S.S. (2009) Profilin oligomerization and its effect on poly (l-proline) binding and phosphorylation Int.J.Biol.Macromol. 45: 265-273

  15. Achary, M.S. and Nagarajaram, H.A. (2009) Effects of Disease Causing Mutations on the Essential Motions in proteins. J. Biomol.Struct.Dyn. 26:609-624

  16. Achary, M.S. and Nagarajaram, H.A. (2008) Comparative docking studies of CYP1b1 and its PCG associated mutant forms. J. Biosci.33:699-713

  17. Md. Tabrez Anwar Shamim, Mohammad Anwaruddin and Nagarajaram, H.A. (2007) Support Vector Machine based classification of protein folds using the structural properties of amino acid residues and amino acid residue pairs. Bioinformatics.23:3320-3327

  18. Suresh B. M. and Nagarajaram, H.A. (2007) IMEx: Imperfect Microsatellite Extractor. Bioinformatics 15 May 2007; 23: 1181 - 1187

  19. The NMITLI-BioSuite Team (Nagarajaram, H.A) (2007) BioSuite: A comprehensive bioinformatics software package (A unique industry academia collaboration) Curr. Sci. 92: 29-38

  20. Sreenu,V.B., Kumar, P., Nagaraju, J. and Nagarajaram, H.A. (2007) Simple sequence repeats in mycobacterial genomes J.Biosci. (A peer-reviewed special issue on Computational Biology) 32: 1-15

  21. M.S. Achary, A. B.M. Reddy, S. Chakrabarti, S.G. Panicker, A.K.Mandal, N.Ahmed, D. Balasubramanian, S.E. Hasnain, and Nagarajaram, H.A. (2006) Disease Causing Mutations in Proteins: Structural Analysis of the CYP1b1 Mutations Causing Primary Congenital Glaucoma in Humans Biophysical J. 91: 4329-4339

  22. Sreenu,V.B., Kumar, P., Nagaraju, J. and Nagarajaram, H.A. (2006) Microsatellite polymorphism across the M. tuberculosis and M. bovis genomes: Implications on genome evolution and plasticity. BMC Genomics 7:78-88 (Highly accessed article)

  23. H.A.Nagarajaram, Prathima Iengar and Indira Ghosh (2005) In silico approach to antimalarial drug discovery: Design of selective inhibitor to Plasmodium falciparum aspartic proteases Frontiers in Biophysics 168-181.

  24. Cheeran, A., Suganthan, R.B., Swapna, G., Bandey, I., Acharya, S., Nagarajaram, H.A. and Sen. R. (2005) E. coli RNA polymerase mutations located near the upstream edge of RNA:DNA hybrid and the beginning of the RNA exit channel are defective for transcription antitermination by N protein from lambdoid phage H-19B J.Mol. Biol 352: 28-43

  25. Prasad,M.D., Muthulakshmi,M., Arunkumar,K.P., Madhu,M., Sreenu,V.B., Pavithra,V., Bose,B., Nagarajaram, H.A., Mita,K., Shimada, T. and Nagaraju, J.(2005) SilkSatDb: A microsatellite database of the silkworm, Bombyx mori. Nucleic Acids Research. 33: D403-D406.

  26. R.K.Gundu, B.Bose, S.Swamynathan, V.B.Sreenu, N.Pavan, S.Acharya and Nagarajaram, H.A (2005) Frontiers in Bioinformatics Research: The Biodiversity Issues "Biodiversity : Status and Prospects" Editors: Pramod Tandon, Manju Sharma and Renu Swarup, Narosa Publishing House, New Delhi.

  27. Ahmed Kamal, G. Ramesh, O. Srinivas, P. Ramulu, N. Laxman ,Tasneem Rehana, M.Deepak, M.S. Achary and Nagarajaram, H.A. (2004). Design, Synthesis, and Evaluation of Mixed Imine-Amine Pyrrolobenzodiazepine Dimers with Efficient DNA-Binding Affinity and Potent CytotoxicityBio-organic & Medicinal Chemistry 12:5427-5436.

  28. Buddhaditta Bose, Gyan Rajkumar, M. Narendar Pavan, A RadhaRama Devi, Nagarajaram, H.A.. (2004) NBSdb: New Born Screening Database Indian Journal of Medical Informatics online.

  29. Sreenu, V.B., Ranjitkumar, G., Swaminathan, S., Priya, S., Bose, B., Narendra Pavan, M., Nagaraju, J., Nagarajaram, H.A. (2004) MICdb - Database of Prokaryotic Microsatellites. Nucleic Acids Research Published in online database issue.

  30. Majeed, A.A., Ahmed, N., Rao, K.R., Ghousunnissa, S., Kausar, F., Bose, B., Nagarajaram, H.A., Katoch, V.M., Cousins, D.V., Sechi, L.A., Gilman, R.H. and Hasnain, S.E. (2004) AmpliBASE MTTM: A Mycobacterium tuberculosis diversity knowledgebase. Bioinformatics 20:989-92.

  31. V.B.Sreenu, G.Ranjitkumar, S.Swaminathan, S.Priya, B.Bose, M.N.Pavan, Geetha Thanu, J.Nagaraju and Nagarajaram, H.A. (2003) MICAS: A fully automated web server for microsatellite extraction and analysis from prokaryote and viral genomic sequences. Applied Bioinformatics 2(3) 165-168.

  32. G Ranjit Kumar, M Narendar Pavan, B. Bose, S Swaminathan, Geetha Thanu, P Prashanthi, B Phani Prasad, V B Sreenu, M Sridhar Achary and Nagarajaram, H.A (2003) EMBnet India Node (EIN) at the Centre for DNA Fingerprinting and Diagnostics: Serving the Indian sub-continent in Bioinformatics Bioinformatics India 1 2:67-77.

  33. V.B.Sreenu, Vishwanath Alevoor, J.Nagaraju and Nagarajaram, H.A (2003) MICdb: Database of Prokaryotic Microsatellites Nucleic Acids Research 31 106-108.

  34. Nagarajaram, H.A. and S.E.Hasnain.(2003) Current Status of Post-Genomics Computational Biology "Computing and Information Sciences : Recent Trends" Editor: J.C.Misra, Narosa Publishing House, New Delhi.

  35. A.Kamal, N. Laxman, G. Ramesh, P. Ramulu, O. Srinivas, K. Neelima, A. K. Kondapi, V. B. Sreenu and Nagarajaram, H.A. 2002 Design, synthesis, and evaluation of new non-cross linking pyrrolobenzodiazepine dimers with efficient DNA-binding ability and potent antitumour activity J. Med. Chem 45 4679-4688.

  36. E.Narayanan, Nagarajaram, H.A., C. Ramakrishnan and N.Srinivasan 2002 Influence of solvent molecules on the stereochemical code of glycine residue PROTEINS 49 326-334.

  37. S.G.Panicker, A.B.M.Reddy, A.K.Mandal,N.Ahmed, Nagarajaram, H.A., S.E.Hasnain and D.B. Balasubramanian 2002 Identification of novel mutations causing familial primary congenital glaucoma in  indian pedigrees Investigative Ophthalmology & Visual Science 43 1358-1366 2002. 

  38. J. Mendes, Nagarajaram, H.A., Cláudio M. Soares, Tom L. Blundell, Maria Arménia Carrondo 2001. Incorporating knowledge-based biases into an energy-based  side-chain   modeling method: application to comparative modeling of protein structure Biopolymers 59:2 72-86.

  39. N. Campillo, Nagarajaram, H.A. & I. Ghosh 2001. Phosphoribosyltransferase superfamily: A comparative structural analysis J.Mol.Model. 7 80-89. 

  40. D.F.Burke<at>, C.Dean<at>, Nagarajaram, H.A.<at>, ... , Tom L.Blundell and  K.Mizuguchi 1999.  An iterative structure-assisted approach to sequence alignment and comparative modeling PROTEINS 3 55-60.  <at>joint first authors.

  41. Nagarajaram, H.A., B.V.B.Reddy and Tom L. Blundell 1999.  Analysis and prediction of inter-strand packing distances between beta-sheets of globular proteins. Protein Eng. 12 1055-1062.

  42. B.V.B.Reddy, Nagarajaram, H.A. and Tom L. Blundell 1999.  Analysis of interactive packing of secondary structural elements in alpha/beta units in proteins Protein Sci. 8 573-586.

  43. R.Sowdhamini, D.F.Burke, Jing-Fei Huang, K.Mizuguchi, Nagarajaram, H.A., N.Srinivasan, R.E.Stewart and Tom L. Blundell 1998. CAMPASS: A database of structurally aligned protein superfamilies Structure 61087-1094.

  44. R.Sowdhamini, D. F. Burke, C. Deane, Jing-Fei Huang, K.Mizuguchi, Nagarajaram, H.A., J.P.Overington, N.Srinivasan, R.E.Steward and Tom L.Blundell 1998.  Protein 3D structural databases: Domains, structurally aligned homologues and superfamilies  Acta Crystallogr. D54 1168-1177.

  45. K.Gunasekaran, Nagarajaram, H.A., C. Ramakrishnan and P. Balaram 1998. Stereochemical punctuation marks in protein structures: Glycine and Proline containing helix stop signals J.Mol.Biol. 275 917-932.

  46. Nagarajaram, H.A., B.V.B.Reddy and T.L.Blundell  1997. Packing of secondary structural elements  in  proteins -  An analysis Prot.Sci. 6 pp87.

  47. R.Sowdhamini, N.Srinivasan, S.Rufino, Nagarajaram, H.A., K.Mizuguchi, D.F.Burke, K.Guruprasad, R.Stewart and T.L.Blundell 1997. Protein domains, superfamilies and functions Prot. Sci. 6 pp75.

  48. R.Sowdhamini, N.Srinivasan, S.Rufino, Nagarajaram, H.A., K.Mizuguchi, D.F.Burke, K.Guruprasad, R.Stewart and T.L.Blundell 1996.  Protein domains, superfamilies and functions Fold. Des., 1(supplement) pp. S59.

  49. R.Varadarajan, Nagarajaram, H.A. and C. Ramakrishnan 1996. A procedure for the prediction of temperature-sensitive mutants of a globular protein based solely on the amino acid sequence  Proc. Natl. Acad. Sci. (USA) 93 13908-13913.

  50. Nagarajaram, H.A. and C. Ramakrishnan 1995.  Stereochemical studies on cyclic peptides - Detailed energy minimisation studies on hydrogen bonded all-trans cyclic pentapeptide backbones J.Biosci. 20 591-611.

  51. Nagarajaram, H.A., R.Sowdhamini, C.Ramakrishnan and P.Balaram 1993. Termination of right handed helices in proteins by the residues in left handed helical conformation FEBS letters 321 79-83.

  52. Nagarajaram, H.A., P.K.Paul, K. Ramanarayanan, K.V.Soman  and C. Ramakrishnan 1992. Conformational studies on beta-bends containing a cis peptide unit Int. J. Peptides Proteins Res. 40 383-394.

  53. Nagarajaram, H.A. and C. Ramakrishnan 1991. Energy minimisation studies on cyclic pentapeptides Indian J. Phys. 65B 449-454
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Last updated on: Wednesday, 25th January, 2012

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