Shekhar Mande (born 1962) completed his M. Sc. In Physics from Nagpur University, Nagpur, and then joined Molecular Biophysics Unit of the Indian Institute of Science, Bangalore to work on the crystal structure of Peanut lectin with Prof. M. Vijayan. The structure, the first of its kind being determined in India, showed an unusual open quaternary structure. After obtaining his Ph. D from the Indian Institute of Science in 1991, he joined Prof. Wim Hol as a post-doctoral fellow at the Rijksuniversiteit Groningen, The Netherlands. In Groningen he was involved in solving a number of structures of triosephosphate isomerases and their complex with inhibitors. These structures showed interesting correlation between protein stability and three- dimensional structure. Later he moved along with Prof. Hol to work at the University of Washington, Seattle, USA, where he was involved in determining the crystal structure of chaperonin-10 from Mycobacterium leprae. In 1995 he took up the job of Scientist C at the Institute of Microbial Technology, Chandigarh. In Chandigarh he established a vibrant group of structural biology of Mycobacterium tuberculosis derived proteins. Since 2001, he has been at CDFD.