Application for

· Exploiting 3D structural templates for detection of metal-binding sites in protein structures

K. Goyal and S. C. Mande

Proteins Struct Funct Bioinform (2007) In press

· PAR-3D: a server to predict protein active site residues (PDF)

K. Goyal, D. Mohanty and S. C. Mande

Nucl. Acids Res. (2007) 35, W503-505.

· BioSuite: A comprehensive bioinformatics software package (A unique industry- academia collaboration) (PDF)

M. Vidyasagar and 111 other authors

Curr. Sci. (2007) 92, 29- 38.

· Inferring genome-wide functional linkages in Escherichia coli by combining improved genome context methods: comparison with high throughput experimental data (PDF)

S. Yellaboina, K. Goyal and S. C. Mande

Genome Res. (2007) 17, 527- 535.

· Multiple gene duplication and rapid evolution in the groEL gene: functional implications (PDF)

K. Goyal, R. Qamra and S. C. Mande

J. Mol. Evol. (2006) 63, 781-787.

· Crystallization and preliminary X-ray crystallographic studies of Mycobacterium tuberculosis CRP/FNR family transcription regulator (PDF)

Mohd. Akif, Y. Akhter, S. E. Hasnain and S. C. Mande

Acta crystallogr. (2006) F62, 873-875.

· The 2.15Å crystal structure of M. tuberculosis chorismate mutase reveals unexpected gene duplication, and suggests a role in host-pathogen interactions (PDF)

R. Qamra, P. Prakash, B. Aruna, S. E. Hasnain and S. C. Mande

Biochemistry (2006) 45, 6997- 7005.

· Cation mediated interplay of loops in Mycobacterium tuberculosis Chaperonin-10 (PDF)

S. Vijaykrishnan, R. Qamra, C. Verma, R. Sen and S. C. Mande

J. Biomolec. Struct. Dyn. (2006) 23, 365- 376. (Cover page)

· Conformational flexibility of M. tuberculosis Thioredoxin reductase: Crystal Structure and Normal Mode Analysis (PDF)

Mohd. Akif, K. Suhre, C. Verma and S. C. Mande

Acta crystallogr. (2005) D61, 1603- 1611.

· The unusual chaperonins of Mycobacterium tuberculosis (PDF)

R. Qamra, S. C. Mande, A. R. M. Coates and B. Henderson

Tuberculosis (2005) 85, 385- 394.

· Effect of alcohols on protein hydration: Crystallographic analysis of hen egg white lysozyme in presence of alcohols (PDF)

A. Deshpande, S. Nimsadkar and S. C. Mande

Acta crytallogr. (2005) D61, 1005-1008.

· Crystallization and preliminary X-ray crystallographic studies of Mycobacterium tuberculosis chorismate mutase (PDF)

R. Qamra, P. Prakash, B. Aruna, S. E. Hasnain and S. C. Mande

Acta crystallogr. (2005) F61, 473-475.

· Crystal Structure of the 65 kDa Heat Shock Protein, Chaperonin 60.2 of Mycobacterium tuberculosis (PDF)

R. Qamra and S. C. Mande

J. Bacteriol. (2004) 186, 8105-8113. (Cover page)

· Mycobacterium tuberculosis GroEL homologues unusually exist as lower oligomers and retain the ability to suppress aggregation of substrate proteins (PDF)

R. Qamra, V. Srinivas and S. C. Mande

J. Mol. Biol. (2004) 342, 605-617

· Expression, purification, crystallization and preliminary X-ray crystallographic studies of Mycobacterium tuberculosis thioredoxin reductase (PDF)

Mohd. Akif, R. Chauhan and S. C. Mande

Acta Crystallogr D (2004) 60, 777-779

· Human recombinant resistin protein displays a tendency to aggregate by forming intermolecular disulfide linkages (PDF)

B. Aruna, S. Ghosh, A. K. Singh, S. C. Mande, V. Srinivas, R. Chauhan, and N. Z. Ehtesham

Biochemistry (2003) 42, 10554- 10559.

· The TB Structural Genomics Consortium: A Resource for TB Biology (PDF)

T. C. Terwilliger, M. S. Park, G. S. Waldo, J. Berendzen, L.-W. Hung, C.-Y. Kim, C. V. Smith, J. C. Sacchettini, M. Bellinzoni, R. Bossi, E. De Rossi, A. Mattevi, A. Milano, G. Riccardi, M. Rizzi, M. M. Roberts, A. R. Coker, P. Tormay, G. Fossati, P. Mascagni, A. R.M. Coates, S. P. Wood, C. W. Goulding, M. Apostol, D. H. Anderson, H. S. Gill, D. S. Eisenberg, B. Taneja, S. C. Mande, E. Pohl, V,. Lamzin, P. Tucker, M. Wilmanns, C. Colovos, W. Meyer-Klaucke, A. W. Munro, K. J. McLean, K. R. Marshall, D. Leys, J. K. Yang, H.-J. Yoon, B. I. Lee, M. G. Lee, J. E. Kwak, B. W. Han, J. Y. Lee,S.-H. Baek, S. W. Suh, M. M. Komen, V. ML. Arcus, E. N. Baker, J. S. Lott, W. Jacobs Jr.,T. Alber, B. Rupp

Tuberculosis (2003) 83, 223- 249.

· Identification of conserved residue patterns in small b- barrel proteins (PDF)

R. Qamra, B. Taneja and S. C. Mande

Prot. Eng. (2002) 15, 967- 77.

· Site directed mutagenesis reveals a novel catalytic mechanism of Mycobacterium tuberculosis Alkylhydroperoxidase C (PDF)

R. Chauhan and S. C. Mande

Biochem J. (2002) 367, 255- 261.

· Function of 90-loop (Thr90-Glu100) region of staphylokinase in plasminogen activation probed through site-directed mutagenesis and loop deletion (PDF)

G. Rajamohan, M. Dahiya, S. C. Mande, K. L. Dikshit

Biochem J. (2002) 365, 379-389.

· The TB Structural genomics consortium: providing a structural foundation for drug discovery (PDF)

C. W. Goulding, M. Apostol, D. H. Anderson, H. S. Gill, C. V. Smith, M. R. Kuo,J. K. Yang, G. S. Waldo, S. W. Suh, R. Chauhan, A. Kale, N. Bachhawat, S. C. Mande, J. M. Johnston, J. S. Lott, E. N. Baker, V. L. Arcus, D. Leys, K. J. McLean, A. W. Munro, J. Berendzen, V. Sharma, M. S. Park, D. Eisenberg, J. Sacchettini, T. Alber, B. Rupp, W. Jacobs, Jr. and T. C. Terwilliger

Curr. Drug Targets- Infect. Dis. (2002) 2, 121- 141.

· Involvement of a nine-residue loop in the generation of the macromolecular substrate-specificity by the activator complex through interaction with substrate kringle domains (PDF)

J. Dhar, A. H. Pande, V. Sundram, J. S. Nanda, S. C. Mande and G. Sahni.

J. Biol. Chem. (2002) 277, 13257- 13267.

· Structure of Mycobacterium tuberculosis chaperonin-10 at 3.5 Å resolution (PDF)

B. Taneja and S. C. Mande

Acta Crystallogr (2002) D58, 260-266.

· Chimeric Vitreoscilla Hemoglobin (VHb) Carrying a Flavoreductase Domain Relieves Nitrosative Stress in Escherichia coli: New Insight into the Functional Role of VHb (PDF)

R. Kaur, R. Pathania, V. Sharma, S. C. Mande and K. L. Dikshit.

Appl. Environ. Microbiol. (2002) 68, 152-160.

· Three- dimensional structure of Mycobacterium tuberculosis chaperonin-10 reveals a partially stable conformation of its mobile loop (PDF)

B. Taneja and S. C. Mande

Curr. Sci. (2001) 81, 87- 91.

· Metal ions modulate the plastic nature of Mycobacterium tuberculosis chaperonin-10 (PDF)

B. Taneja and S. C. Mande

Prot. Eng. (2001) 14, 391- 395. (Cover page)

· Characterization of the Mycobacterium tuberculosis H37Rv alkyl hydroperoxidase AhpC points to the importance of ionic interactions in oligomerization and activity (PDF)

R. Chauhan and S. C. Mande

Biochem J. (2001) 354, 209- 215.

· Genomics and novel drug targets (PDF)

B. Taneja, R. Chauhan and S. C. Mande

In Current R & D Highlights, CDRI, Lucknow. (2000) ed. H. S. Subramanya. 23, 6- 11.

· Homology modelling of a novel xylanase: molecular basis of high thermostability and alkaline stability

S. S. Mande, N. Gupta, A. Ghosh and S. C. Mande.

J. Biomolec. Str. Dyn. (2000) 18, 137- 144.

· Complex evolution of the inositol-1-phosphate synthase gene among archaea and eubacteria (PDF)

N. Bachhawat and S. C. Mande

Trends Genet. (2000) 16, 111- 113.

· Structural characterization of protein denaturant interactions: crystal structures of hen egg white lysozyme in complex with guanidinium chloride and DMSO (PDF)

S. C. Mande and M. E. Sophia.

Prot Eng. (2000) 13, 133- 141.

· Function of the central domain of streptokinase in substrate plasminogen docking and processing revealed by site-directed mutagenesis (PDF)

A. Chaudhary, S. Vasudha, K. Rajagopal, S. S. Komath, N. Garg, M. Yadav, S. C. Mande and G. Sahni.

Prot. Sci. (1999) 8, 2791- 2805.

· Conserved structural features and sequence patterns in the GroES fold family (PDF)

B. Taneja and S. C. Mande.

Prot. Eng. (1999) 12, 815- 818.

· Identification of the ino1 gene of Mycobacterium tuberculosis H37Rv reveals a novel class of inositol-1-phosphate synthase enzyme (PDF)

N. Bachhawat and S. C. Mande.

J. Mol. Biol. (1999) 291, 531-536.