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Dr.Sangita Mukhopadhyay
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Home » Molecular Cell Biology » Publications
Molecular Cell Biology
Publications

  • S. Mukhopadhyay**, S.Nair and S. Ghosh** (2011). Pathogenesis in tuberculosis: transcriptomicapproaches to unraveling virulence mechanisms and finding new drug targets. FEMS Microbiology Reviews (In Press)(**Corresponding Author)

  • S. Mukhopadhyay* and K. N. Balaji* (2011). The PE and PPE proteins of Mycobacterium tuberculosis. Tuberculosis (In Press)

  • A. Das and S. Mukhopadhyay* (2011). The evil axis of obesity, inflammation and type-2 diabetes. Endocrine, Metabolic & Immune Disorders - Drug Targets 11:23-31 (*Corresponding Author)

  • S. Nair, A. D. Pandey and S. Mukhopadhyay* (2011). The PPE18 protein of Mycobacterium tuberculosis inhibits NF-kB/rel-mediated proinflammatory cytokine production by upregulating and phosphorylating SOCS3 protein. Journal of Immunology 186: 5413-5424 (*Corresponding Author)

  • K. Alam, S. Ghousunnissa, S. Nair, V. L. Valluri and S. Mukhopadhyay* (2010). Glutathione-redox balance regulates c-rel-driven IL-12 production in macrophages: possible implications in anti-tuberculosis immunotherapy. Journal of Immunology 184:2918-2929.(*Corresponding Author)

  • S. Nair, P. A. Ramaswamy, S. Ghosh, D. C. Joshi, N. Pathak, I. Siddiqui, P. Sharma, S.E. Hasnain, S.C. Mande and S. Mukhopadhyay* (2009) The PPE18 of Mycobacterium tuberculosis interacts with TLR2 and activates IL-10 induction in macrophage. Journal of Immunology 183:6269-6281.(*Corresponding Author).

  • N. Bashir, F. Kounsar, S. Mukhopadhyay and S. E. Hasnain (2010). Mycobacterium tuberculosis conserved hypothetical protein rRv2626c modulates macrophage effector functions. Immunology 130:34-45.

  • M. A. Hussain, S. A. Naveed, L. A. Sechi, S. Ranjan, A. Alvi, I. Ahmed, A. Ranjan, S. Mukhopadhyay and N. Ahmed (2008). Isocitrate dehydrogenase of Helicobacter pylori potentially induces humoral immune response in subjects with peptic ulcer disease and gastritis. PLoS ONE. 3:e1481.

  • S. Tundup, N. Pathak, M. Ramanadham, S. Mukhopadhyay, K. J. Murthy, N. Z. Ehtesham, and S. E. Hasnain (2008). The co-operonic PE25/PPE41 protein complex of Mycobacterium tuberculosis elicits increased humoral and cell mediated immune response. PLoS ONE. 3:e3586.

  • N. Khan, K. Alam, S. Nair, V. L. Valluri, K.J. R. Murthy and S. Mukhopadhyay* (2008). Strong immune responses to the PPE protein Rv1168c are associated with active tuberculosis disease. Clinical and Vaccine Immunology 15:974-980.(*Correspondig Author)

  • N. Khan, K. Alam, S. C. Mande, V. L. Valluri, S. E. Hasnain and S. Mukhopadhyay* (2008). Mycobacterium tuberculosis heat shock protein 60 modulates immune response to PPD by manipulating the surface expression of TLR2 on macrophages. Cellular Microbiology 10:1711-1722.(*Corresponding Author)

  • N. Khan, S. Ghousunnissa, S. M. Jegadeeswaran, D. Thiagarajan, S. E. Hasnain, and S. Mukhopadhyay* (2007). Anti-B7-1/B7-2 antibody elicits innate-effector responses in macrophages through NF-kB-dependent pathway. International Immunology 19:477-486(*Corresponding Author)

  • S. Mukhopadhyay*, S. Nair, and S. E. Hasnain (2007) Nitric oxide: Friendly rivalry in tuberculosis. Current Signal Transduction Therapy 2:121-28(*Corresponding Author).

  • C. S. Boddupalli, S. Ghosh, S. S. Rahim, S. Nair, N. Z. Ehtesham, S. E.. Hasnain and S. Mukhopadhyay* (2007). Nitric oxide inhibits interleukin-12 p40 through p38 MAPK-mediated regulation of calmodulin and c-rel. Free Radical Biology and Medicine 42:686-497(*Corresponding Author)

  • N. Khan, S. S. Rahim, C. S. Boddupalli, S. Ghousunnissa, S. Padma, N. Pathak, D. Thiagarajan, S. E. Hasnain and S. Mukhopadhyay* (2006). Hydrogen peroxide inhibits IL-12 p40 induction in macrophages by inhibiting c-rel translocation to the nucleus through activation of calmodulin protein. Blood 107:1513-1520(* Corresponding Author)

  • S. S. Rahim, N. Khan, C. S. Boddupalli, S. E. Hasnain and S. Mukhopadhyay* (2004). IL-10 mediated suppression of IL-12 production in RAW 264.7 cells also involves c-rel transcription factor. Immunology 114:313-321

  • N. Silswal, A. K. Singh, B. Aruna, S. Mukhupadhyay, S. Ghosh, and Z. Ehtesham (2005). Human resistin stimulates the pro-inammatory cytokines TNF-α and IL-12 in macrophages by NF-kB-dependent pathway. Biochemical and Biophysical Research Communications 334:1092-1101.

  • S. Ghosh, S. Rasheedi, S. S. Rahim, S. Banerjee, R. K. Choudhary, P. Chakhaiyar, N. Z. Ehtesham, S. Mukhopadhyay and S. E. Hasnain (2004). Method for enhancing solubility of the expressed recombinant proteins in Escherichia coli. Biotechniques 37:418-423.

  • S. Mukhopadhyay*, V. M. L. Srivastava, P. K. Murthy and S. E. Hasnain (2004) Poorer NF-kB signaling by microfilariae in macrophages from BALB/c mice affects their ability to produce cytotoxic levels of nitric oxide to kill microfilariae. FEBS Letters 567:275-280 (* Corresponding Author)

  • R. K. Choudhary, S. Mukhopadhyay, P. Chakhaiyar, N. Sharma, K. J. R. Murthy, V. M. Katoch and S. E. Hasnain (2003). PPE antigen Rv2430c of Mycobacterium tuberculosis induces a strong B cell response. Infection Immunity 71:6338-6343.

  • M. D. Bashyam and S. Mukhopadhyay (2003). Status of Tuberculosis in India-2003 (R. Nayak, M. S. Shaila and G. R. Rao eds.) and Trends in Malaria and Vaccine Research: The current Indian Scenario (D. Raghunath and R. Nayak eds.). Book Review, Infection, Genetics and Evolution 3:75-77.

  • Ghosh, S., Singh, A. K., Aruna, B., S. Mukhopadhyay, and Ehtesham, N. Z. (2003). The genomic organization of mouse resistin reveals major difference from the human resistin. Gene 305:27-34

  • S. Bhatia, S. Mukhopadhyay, E. Jarman, G.Hall, A. George, S. Rath, J. R. Lamb, and V. Bal, (2002). Scavenger receptor-specific allergen delivery elicits IFN-g-dominated immunity and directs established Th2-dominated responses to a non-allergic phenotype. Journal of allergy and clinical immunology, 109:321-328.

  • S. Mukhopadhyay**, M. Mohanty, A. Mangla, A. George, V. Bal, S. Rath, and B. Ravindran (2002). Macrophage effector functions controlled by Bruton's tyrosine kinase are more crucial for microfilarial clearance than the cytokine balance of T cell responses. Journal of Immunology 168:2914-2921.

  • B. Ravindran, P. K. Sahoo, M. Mohanty, S. Mukhopadhyay and A. P. Dash (1999) Increased susceptibility of mice with XID mutation to Brugia malayi infection. Medical Science Research, 27:135-137.

  • S. Mukhopadhyay**, P. K. Sahoo, A. George, V. Bal, S. Rath and B. Ravindran (1999) Delayed clearance of filarial infection and enhanced Th1 immunity due to modulation of macrophage APC functions in xid mice. Journal of Immunology, 163:875-883.

  • S. Mukhopadhyay**, A. George, V. Bal, B. Ravindran and S. Rath (1999). Bruton's tyrosine ki-nase deficiency in macrophages inhibits nitric oxide generation leading to enhancement of interleukin-12 induction. Journal of Immunology, 163:1786-1792.

  • S. Mukhopadhyay**, A. P. Dash & B. Ravindran (1996) Setaria digitata in Mastomys coucha : An animal model for chemotherapeutic and immunobiological studies. Parasitology, 113, 323-330.

  • S. Mukhopadhyay** & B. Ravindran (1997) Antibodies to diethylcarbamazine potentiate the anti-filarial activity of the drug. Parasite Immunology, 19. 191-195.

    (*Corresponding Author)

    (**First Author)

    • List of Patents taken

  • S. Mukhopadhyay, K. H. Bhat and N. Khan. Methods for Identifying inhibitors of Rvxxx (filed in India [24 Nov 2008]).

  • S. Mukhopadhyay, K. H. Bhat and N. Khan. Inhibitors of Rv0256c. (filed in USA, [USPTO, 31Aug 2009]). Application number: 12/551,115; Publication number: US 2010/0129809 A1; Filing date: 31Aug2009;
    http://www.google.co.in/patents?hl=en&lr=&vid=USPATAPP12551115&id=qlzRAAAAEBAJ&oi=fnd&dq=sangita+mukhopadhyay&printsec=abstrac)

  • S. Mukhopadhyay and N. Khan. Detection of Mycobacterium tuberculosis (filed in USA [USPTO, 19 Dec 2008]). http://www.freepatentsonline.com/y2010/0159485.html.
    http://www.google.co.in/patents?hl=en&lr=&vid=USPATAPP12339524&id=a4XVAAAAEBAJ&oi=fnd&dq=sangita+mukhopadhyay&printsec=abstract

    • Awards, fellowships and honors

  • National Scholarship, 1988-1989 by Ministry of Education, Government of India.

  • Gold medal in M.Sc.

  • `Jawaharlal Nehru Memorial Fund Award' 1993 In Recognition of Academic Excel-lence.

  • Apeeza Trust Award, 1996 by Indian Immunology Society, India.

  • Best Young Scientist Award, 1997 by Indian Immunology Society, India.

  • Best Poster Award, 2002 by `Indian Immunology Society & Symposium on Immunopa-rasitology', India.

  • Young Scientist SERC Fast Track Grant Award, 2003 by Department of Science and Technology, Govt of India.

  • Third World Women Scientist Grant Award, 2003 by TWAS, Italy.

  • Young Women Bioscientists of Promise Award, 2004 by the Indian Science Congress Association, India.

  • DBT Overseas Associateship Award, 2005 by DBT, Govt of India.

  • Membership of American Society of Hematology (ASH), USA, 2007 till date.

  • National Young Woman Bioscientist Award, 2007 by DBT, Govt of India.

  • National Bioscience Award for Career Development for the year 2008 by Department of Biotechnology (DBT), Govt of India

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    Contact Information
    Email: sangita<at>cdfd.org.in
    Phone: +91-40-24749423
    Fax: +91-40-24785447
    Last updated on: Monday, 5th September, 2011.

    Copyright @ 2008 CDFD.