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Dr. Murali Bashyam
Research
Molecular Oncology Group
Publications
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Home » Molecular Oncology » Publications
Molecular Oncology
Publications
  • AH Shain, CP Giacomini, K Matsukuma, CA Karikari, MD Bashyam, M Hidalgo, A Maitra, JR Pollack. Convergent structural alterations define SWI/SNF chromatin remodeler as a central tumor suppressive complex in pancreatic cancer. Proc Natl Acad Sci, USA. 2012, 109:E252-E259.

  • M D Bashyam, A K Chaudhary, E C Reddy, V Reddy, V Acharya, H A Nagarajaram, A R R Devi, L Bashyam, A B Dalal, N Gupta, M Kabra, M Agarwal, S R Phadke, R Tainwala, R Kumar, S V Hariharan (2012). An Ectodysplasin A receptor (EDAR) founder mutation results in a high frequency of the autosomal recessive form of Hypohidrotic Ectodermal Dysplasia in India. Br J Dermatol (In Press).

  • Murali Bashyam, Guroji Purushotham, Ajay K Chaudhary, Madhumohan Rao, Vishal Acharya, Tabrez Mohammad, Hampapatalu Nagarajaram, Vuppaladadhiam Hariram, Calambur Narasimhan. A low prevalence of MYH7/MYBPC3 mutations among Familial Hypertrophic Cardiomyopathy patients in India. Mol Cell Biochem 2012, 360:373-382.

  • Kwei KA, Shain AH, Bair R, Montgomery K, Karikari CA, van de Rijn M, Hidalgo M, Maitra A, Bashyam MD, Pollack JR. SMURF1 Amplification Promotes Invasiveness in Pancreatic Cancer. PLoS One 2011;6(8):e23924.

  • Nirmala Yabaluri* and Murali D Bashyam*. 2010. Hormonal regulation of gluconeogenic gene transcription in the liver. J Biosci 35:473-484 *shared corresponding authorship.

  • Bashyam MD, Chaudhary A, Reddy E, RamaDevi A, Savithri G, Ratheesh R, Bashyam L, Mahesh E, Sen D, Puri R, Verma I, Nampoothiri S, Vaidyanathan S, Chandrasekhar M, Kantheti P. 2010. Phenylalanine hydroxylase gene mutations in phenylketonuria patients from India: identification of novel mutations that affect PAH RNA. Mol Genet Metabolism 100:96-99.

  • Angalena R, Prabitha KN, Chaudhary AK, Bashyam MD, Dalal AB. A novel homozygous point mutation at codon 82 (HBB:c.247A > T)) in the beta-globin gene leads to thalassemia major. Int J Lab Hematol 2010 Oct;32(5):548-549 http://www.ncbi.nlm.nih.gov/pubmed/20136848

  • Murali D BAshyam (2010), G Purushotham, K Madhumohan, Mohammad Anwaruddin,H.A Nagarajaram, Vuppaladadhiam Hariram,Calambur Narasimhan. the MYH7 p.R787H mutation causes hypertrophic cardiomyopathy in two unrealted families.Exp clin Cardiol 2010;15(1):e1-e4.

  • Murali D Bashyam,Angalena R, Ajay Chaudhary, Ashwin Dalal. Hemoglobin D (Iran) masquerading as Hemoglobin E: An interesting case report. Newsletter of Genetics Chapter of Indian Academy of Pediatrics, Vol 2, Issue 1 (Jan-Mar 2009).

  • Bashyam MD. Nonsense -mediated decay: linking a basic cellular process to human disease. Expert Rev Mol Diagn. 2009 May;9(4):299-303.

  • Murali D Bashyam, Senthil Kumar, Aruna Ramachandran and Seyed E Hasnain. (2009). Octamer and heat shock elements regulate transcription from the AcMNPV polyhedrin gene promoter. Arch Virol 154:445-456

  • Murali D Bashyam. (2009). Studies on nonsense mediated decay reveal novel therapeutic options for genetic diseases. Recent patents on DNA & Gene Sequences 3:7-15i

  • Murali D Bashyam and R Ratheesh. 2008. Genetic instability in colorectal cancer. ICFAI Journal of Biotechnology, 2:13-26.

  • Kevin A. Kwei*, Murali D. Bashyam*#, Jessica Kao, Raman Ratheesh, Edumakanti C. Reddy, Young H. Kim, Kelli Montgomery, Craig P. Giacomini, Yoon-La Choi1, Sreejata Chatterjee, Collins A. Karikari, Keyan Salari1, Pei Wang6, Tina Hernandez-Boussard, Gowrishankar Swarnalata, Matt van de Rijn, Anirban Maitra, Jonathan R. Pollack#. 2008. Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer. PLOS-Genetics, 4:e100081.
    * shared first authorship
    # shared senior authorship


  • M D Bashyam, A RadhaRama Devi, C K Reddy and S Ranjan. 2007. Molecular genetic analysis of Hypohidrotic Ectodermal Dysplasia patients from India reveals novel mutations in the EDA and EDAR genes. Br J Dermatol 158:163-167.

  • Bashyam M. D. and S. E. Hasnain.; Array-based Comparative Genomic Hybdidization: applications in cancer and tuberculosis; in Bioarrays, Ed K Appasani, Humana Press, 2007, pp 107-121.

  • M D Bashyam, G R Savithri, M Gopikrishna, C Narasimhan. 2007. A p.R870H mutation in the beta cardiac myosin heavy chain 7 gene causes Familial Hypertrophic Cardiomyopathy in several members of an Indian family. Canad J Cardiol.23:788-790

  • MD Bashyam, A RadhaRama Devi, M Gopikrishna, R Ratheesh, G Savithri and G Swarnalata. (2006). Farber lipogranulomatosis-clinical and molecular genetic analysis reveals a novel mutation In an Indian family. J Hum Genet 51:811-814.

  • Bashyam M D, Ryan Bair, Young H Kim, Pei Wang, Tina Hernandez-Boussard, Trobert Tibshirani, Anirban Maitra, Jonathan R. Pollack. Array-based comparaative genomic hybridization identifies localized DNA ampilfications and homozygous deletions in pancreatic cancer. Neoplasia, 7:556-562.

  • Murali Dharan Bashyam, Leena Bashyam, Gorinabele R Savithri, Munimanda Gopikrishna, Vartul Sangal, Akela Radha Rama Devi. (2004) Molecular genetic analyses of b-thalassemia in South India reveals rare mutations in the b-globin gene. Journal of Human Genetics, 49:408-413.

  • M D Bashyam and S E Hasnain. (2004) The extracytoplasmic function sigma factors: role in bacterial pathogenesis. Infection, Genetics and Evolution 4:301-308.

  • Bashyam, M.D., Viswanathan, P., Venkaiah, B., Kumar, S., Rasheedi, S., Vrati S. and Hasnain, S.E. (2003) The homologous region sequence (hr1) of Autographa californica multinucleocapsid polyhedrosis virus can enhance transcription from non-baculoviral promoters in mammalian cells. Journal of Biological Chemistry 278: 52564 - 52571

  • Bashyam, M. D. and S. E. Hasnain (2003) The human genome sequence: impact on health care. Ind. J. Med. Res. 117:43-65.

  • Bashyam, M. D. (2003). Prokaryotic Genomes (Michel Blot ed.). Book Review, Current Science, 84:1366-1367. *

  • Murali D Bashyam, Gorinabele R Savithri, Murugapiran S Kumar, Calambur Narasimhan and Pratibha Nallari (2003). Molecular genetics of familial hypertrophic cardiomyopathy (FHC). J. Hum. Genet. 48:55-64.

  • Bashyam, M. D. and S. Mukhopadhyay (2003). Status of Tuberculosis in India-2003 (R. Nayak, M. S. Shaila and G. R. Rao eds.) and Trends in Malaria and Vaccine Research: The current Indian Scenario (D. Raghunath and R.Nayak eds.). Book Review, Infection, Genetics and Evolution 3:75-77. *

  • Bashyam, M. D. (2002). Microarrays for the Neurosciences : An essential guide. Daniel H. Geschwind and Jeffery P. Gregg (eds.). Book Review, Current Science 83:649-650. *

  • Bashyam, M. D. (2002) Understanding cancer metastasis: An urgent need for using differential gene expression analysis. Cancer 94:1821-1829.

  • M. D. Bashyam, Ramachandran, A., P. Viswanathan, S. Ghosh, M. S. Kumar, S. E. Hasnain. (2001). The bountiful and baffling baculovirus: The story of polyhedrin transcription. Current Science 81:998-1010.

  • M. D. Bashyam, Ramachandran, A., A. Jain, P. Arora, U. Chatterjee, S. Ghosh, V. K. Parnaik, and S. E. Hasnain. (2001) Novel Sp family-like transcription factors are present in adult insect cells and are involved in transcription from the polyhedrin gene initiator promoter. J. Biol. Chem.276:23440-23449.

  • Bashyam, M. D., S. Ghosh, A. Ramachandran, P. Viswanathan, S. E. Hasnain. (2000) Multiple regulatory circuits for transcription from the polyhedrin gene promoter of the Autographa californica  multiple nucleocapsid nuclear polyhedrosis  virus. Proc. Indian Natn. Sci. Acad. (PINSA) B66 Nos 2&3 pp 83-96.

  • Bashyam, M. D. and A. K. Tyagi (1998) Identification and analysis of "extended -10" promoters from mycobacteria. J. Bacteriol. 180:2568-2573.

  • Bashyam, M. D., D. Kaushal, S. K. Dasgupta  and A. K. Tyagi (1996) A study of the mycobacterial transcriptional apparatus: identification of novel features in promoter elements. J. Bacteriol. 178:4847-4853.

  • Bashyam, M. D. and A. K. Tyagi (1994) An efficient and high yielding method for isolation of RNA from mycobacteria. Biotechniques 17:834-836.

  • M. D. Bashyam, Dasgupta, S. K. and A. K. Tyagi (1993) Cloning and assessment of mycobacterial promoters by using a plasmid shuttle vector. J. Bacteriol. 175:5186-5192.
  • Awards
  • 'Faculty from developing countries’ award from American Association for Cancer Research to attend the 2nd International Dead Sea Conference on 'Advances in cancer research; from the laboratory to the clinic', Jordan, March 7-10, 2010.

  • Awarded the National Cancer Institute (NCI), USA Fellowship to attend the Cancer Prevention Summer Curriculum Courses conducted by the NCI, 2009.

  • American Association for Cancer Research National Cancer Institute (AACR-NCI) International investigator opportunity grant, 2008.

  • Selected as a member of the multidisciplinary young scientist team, by the Indian National Science Academy and Department of Science and Technology, Government of India, to shape the future of Indian Science (2008).

  • Fogarty International Research Collaboration Award, Fogarty International Center, National Institutes of Health, USA, 2008.

  • Indian National Science Academy (INSA), Govt of India, travel grant to present abstract at the Cold Spring Harbor Meeting on Mechanisms and Models of Cancer (Aug 16-20, 2006).

  • Department of Science and Technology (DST), Govt of India, travel fellowship to present abstract at the Cold Spring Harbor Meeting on Mechanisms and Models of Cancer (Aug 16-20, 2006)

  • .
  • International Cancer Technology Transfer Fellowship (ICRETT) of the International Union Against Cancer (UICC), 2005

  • Sir Dorabji Tata Trust travel award, 2005

  • The Overseas Associateship Award of the Department of Biotechnology, 2003

  • Young Scientist Award of the Department of Science and Technology, 2001

  • Sir Jamsetji Tata Trust Award for training in Microarray Technology at the Memorial Sloan Kettering Cancer Center, New York, USA, 2000

  • Sir Dorabji Tata Trust Award for training in Microarray Technology at the Memorial Sloan Kettering Cancer Center, New York, USA, 2000

  • Young scientist medal of the Indian National Science Academy (INSA) for the year 1998

  • Post-Doctoral Fellowship at the National Institute of Immunology, New Delhi, November 1997 to November, 1999

  • Young scientist award of the Association of Microbiologists of India for the year 1995
  • Contact Information
    Email: bashyam<at>cdfd.org.in
    Phone: +91-40-24749383
    Fax: +91-40-24749448
    Last updated on : Tuesday, 7th February, 2012.

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