Home | Site Map | Contact Us | Hindi Version
About Us Services Research Publications Group Leaders RTI Act Awards & Honours Careers Web Mail
 
Dr. Murali Bashyam
Research Interests
Molecular Oncology Group
Publications
Past Members
Awards, Fellowships and Honours
 
Home » Molecular Oncology » Research
Molecular Oncology
Clinical and molecular genetic analysis of squamous cell carcinoma of the tongue

Squamous cell carcinoma of the tongue (SCCT) is a unique subtype of head and neck cancer because of its relatively higher incidence in the younger age group as well as in nonsmokers. It is also significantly more aggressive than other Head and Neck cancers due to a propensity for rapid metastatic spread. We have performed a comprehensive genomic and clinico-pathological analysis of SCCT that has unraveled a unique cross talk between P53 mutation and status of codon 72 polymorphism. We are currently pursuing genome-wide chromatin immunoprecipitation and RNA seq analysis to identify and characterize possible differential transcriptional targets of mutant and wild type P53.

People involved
  • Raju SR Adduri : SRF; travel award from the GP Talwar Immunology Foundation to present work at the annual AACR meeting, San Diego, USA, 2014.
  • K Viswakalyan : Research Assistant
  • K Padmavathi : Project JRF
  • Anupama Shirke : Project JRF
Funding Agencies : ICMR; CSIR
Contact Information
Email: bashyam<at>cdfd.org.in

Phone: +91-40-24749383
Fax: +91-40-24749448
Last updated on : Tuesday, 14th July, 2015.

Copyright @ 2008 CDFD.