Symposium on Macromolecular Crystallography

Centre for DNA Fingerprinting and Diagnostics

November 15-16, 2005

 

Scientific Programme

 

November 15, 2005

 

Inaugural Session

 

9:00 am

Welcome

Shekhar Mande and Seyed Hasnain

Opening remarks

M. Vijayan

Vote of thanks

R. Sankaranarayanan

 

Session I: Hot Structures- I

Session Chair:  M. Vijayan

 

9:15 am

Structural basis for invasion of malaria parasites into human red blood cells

Amit Sharma

9:40 am

Structure of l CII: Implications for recognition of direct repeat DNA by an unusual tetrameric organization

Pradeep Parrack

10:05 am

Inverting enantioselectivity in domains responsible for enforcing homochirality during translation

Shobha Kruparani

10:30 am

Crystal Structure Of MLD Containing Disintegrin From Saw-Scaled     (Echis carinatus) Venom at 3.2 Å Resolution

Md Imtaiyaz Hassan

 

Tea Break

 

 

Session II: Methods in Macromolecular Crystallography

Session Chair: J K Dattagupta

 

11:30 am

Two step strategy for crystallization of membrane proteins

S. Palanivelu

11:55 am

Use of Single Wavelength Anomalous Diffraction in Determining Macromolecular Structures

D. Velmurugan

12:20 pm

Conformational Flexibility of M. tuberculosis Thioredoxin reductase: Crystal Structure and Normal Mode Analysis

Mohd. Akif

 

Lunch Break

 

 

1:45- 3:45

Poster session

 

 

Session III: Industry Session

Session Chairs: H. Subramanya and Sharmila Mande

 

3:45 pm

Automation and miniaturization of protein crystallization

Jo Butlin

4:00 pm

Improving data quality- without having to grow new crystals

E. R. Hovestreydt

4:15 pm

New detectors for X-ray crystallography

Goeran Helgesson

4:30 pm

Development of BioSuite: model for Industry- Academia partnership

Sharmila Mande

4:45 pm

Approaches in structure guided drug design

Ramesh Sistla

 

Special session to commemorate

Platinum Jubilee of the National Academy of Sciences, India

 

Programme

 

Remarks by Session Chairperson

S. E. Hasnain

 

Historical Profile of Macromolecular Crystallography in India through Publications

by

M. Vijayan

 

Plenary talk

High-throughput structural biology and structure-based drug design against breast cancer

by

T. P. Singh

 

Venue:

Centre for DNA Fingerprinting and Diagnostics, Gandipet Complex

 

 

Date and time:

15th November 2005

5:30 pm

 

7:00 pm onwards

Banquet dinner

 


November 16, 2005

 

Session IV: Nucleic acid-binding and viral proteins

Session Chair: Dinakar Salunke

 

9:00 am

Structure- activity studies on nucleotide cyclases from Mycobacterium tuberculosis

K. Suguna

9:25 am

Structure, interaction and plasticity of M.tuberculosis RuvA

J. Rajan Prabu

9:50 am

Structural studies on physalis mottle virus: structures of bottom component encapsidating genomic RNA and empty top component

S. Someswar Rao

10:15 am

Crystal Structure of the Serine Protease Domain of Sesbania Mosaic Virus polyprotein

P. Gayathri

10:40 am

NAD+ -dependent DNA ligase (Rv3014c) from Mycobacterium tuberculosis: structure-function relationship and novel specific inhibitors

Ravishankar Ramachandran

 

Tea break

 

 

Session V: Protein ligand interactions

Session Chair: B. Gopal

 

11:30 am

Crystal structure of tethered HIV-1 protease complexed to a decapeptide substrate

M. V. Hosur

11:55 am

Unusual sugar specificity of banana lectin from Musa paradisiaca and its probable evolutionary origin. Crystallographic and modelling studies

D. D. Singh

12:20 pm

Structural evidence for mercury inhibition of D-hydantoinase

K.V. Radha Kishan

12:45 pm

Differential antigen-juxtapositioning within the paratope enhances germline antibody pluripotency: Crystallographic analysis of germline antibody 36-65 in complex with three independent antigens

Dhruv K Sethi

1:10 pm

Structure of d(CGCGCA).d(TGCGCG) in two crystal forms: cobalt and ruthenium hexammine ion interactions

N. Gautham

 

Lunch Break

 

Session VI: Hot Structures- II

Session Chair: C. G. Suresh

 

2:15 pm

Crystal structure of low-molecular-weight protein tyrosine phosphatase from Mycobacterium tuberculosis

Amit Kumar Das

2:40 pm

Structural basis of thermostability of Bacillus subtilis lipase

E. Rajakumara

3:05 pm

Crystal Structures of ADP and AMPPNP-bound Propionate Kinase (TdcD) from Salmonella typhimurium

Dhirendra K. Simanshu

3:30 pm

Crystal structure of NP24-I, an antifungal, salt-induced protein from tomato fruits

Chandana Chakrabarti